Abstract:
The research was conducted to estimate the chemical composition of plant legumes, which are
highly protein such as Indian fenugreek, white lupine seeds and yellow lentil, seeds The study
also was evaluated of the protective effects of feeding legume seeds supplement diets on
experimental Hyperuricemic rats. The supplemented diet on Potassium oxonate 2% were
increased blood level of uric acid, which caused Hyperuricemia . Sixty different male adult rats
randomly weighing 160+_8. were separated to six groups: One group were consisted of 10 rats
serving as a control negative group (-ve), were feeding on regular diet only, at the same time the
fifty others separated per fife groups, (ten rats in each one) feed them same intake contains 2%
of potassium oxonate for 6 weeks earlier than starting the experiment. The Hyperuricemia
groups were divided to:- 1- control group +v (fed stander diet only) 2- white lupine group
(which fed stander diet plus 10% white lupine seed powder). 3- yellow lentil group (which fed
10% yellow lentil in average diet), 4- (white lupine seed 5% plus 5% dried leaves fenugreek
powder in standard diet group) 5- (yellow lentil 5% plus 5% powder of fenugreek seeds in
standard diet group.) After two months Hyperuricemic rats which feed scheduled diet
supplement.
Potassium oxonate 2% were sacrificed to taking blood samples for analysis. The results observed
that the control rat groups -ve nonsignificant differences in nutritional result compared with
Hyperuricemic rat groups which fed on diet addition fenugreek with white lupine and lentil.
Hyperuricemic rats which treatment with legumes seed powder (white lupine, lentil and the
mixer with fenugreek) were recorded significantly decreased in urea, uric acid, creatinine and
(NO) nitric oxide, while resulting significantly increased in albumin globulin, total protein,
antioxidant enzymes as SOD, Catalase, GPX and Immunoglobulin (Ig M and Ig G), in compared
with control positive group (+ve). The conclusion of this search prove that the diet added the two
rich protein-legume such as white lupine with a fenugreek or lentil with the fenugreek, had an
enhancement effect on nutritional dietary, biochemical analysis. and increases the immunity per antioxidant activity. thus So its considered good treatment to high uric acid, purines, and
Hyperuricemia, which are causes of gout.
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